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Hematologist in Cyprus warns against plasmapheresis outside specialized centers

UA.NEWS 11 September 2026 04:28
Hematologist in Cyprus warns against plasmapheresis outside specialized centers

Hematologist Sotiris Koumas in Cyprus warned that plasmapheresis should be performed only for established therapeutic indications and in specialized medical centers. According to him, the procedure can cause complications of varying severity, from mild to serious, Cyprus Mail reports.

When the procedure is used

Plasmapheresis is used, among other fields, in hematology and neurology. It involves removing and replacing plasma — the liquid component of blood that carries proteins, antibodies and clotting factors. Koumas explained that pathological proteins, autoantibodies or other potentially harmful substances may accumulate in plasma in certain diseases.

As an example, the doctor cited thrombotic thrombocytopenic purpura, in which plasmapheresis may be necessary. He stressed that early diagnosis and the start of treatment, when hours may matter, can be decisive for the patient's survival. Such treatment may require cooperation between hematologists, nephrologists, intensive care specialists, surgeons and specialized medical staff.

Possible complications

Among the risks, Koumas named injuries or bleeding during catheter insertion. A catheter that remains in place during treatment may become infected or contribute to the formation of a blood clot.

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During the procedure, the patient's blood passes through a special machine that separates and removes plasma, after which the blood cells are returned to the patient. A replacement fluid is administered to compensate for the removed plasma; depending on the indication and method, this may be donor plasma. As a biological product, it can cause allergic reactions requiring anything from anti-allergy medication to more serious medical intervention.

A drop in blood pressure and electrolyte imbalances are also possible, which in some cases may lead to arrhythmia. Koumas noted that these known risks can be managed in an appropriate hospital setting.

Question of use for rejuvenation

The hematologist's comment came amid public discussions following the death of Yorgos Mazonakis and reports linking plasmapheresis to rejuvenation procedures. Koumas said he was not aware of plasmapheresis being used in Cyprus for this purpose and indicated that competent authorities should provide information about the practices and their compliance with approved scientific protocols.

He added that Cyprus' Ministry of Health is responsible for regulatory requirements for centers offering such procedures. According to the doctor, facilities must meet the requirements to obtain a license, and inspections of their activities should be strengthened.

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